labarchive-integration
Electronic lab notebook API integration. Access notebooks, manage entries/attachments, backup notebooks, integrate with Protocols.io/Jupyter/REDCap, for programmatic ELN workflows.
statsmodels
Statistical modeling toolkit. OLS, GLM, logistic, ARIMA, time series, hypothesis tests, diagnostics, AIC/BIC, for rigorous statistical inference and econometric analysis.
Full skill instructions
Statsmodels is Python's premier library for statistical modeling, providing tools for estimation, inference, and diagnostics across a wide range of statistical methods. Apply this skill for rigorous statistical analysis, from simple linear regression to complex time series models and econometric analyses.
This skill should be used when:
import statsmodels.api as sm
import numpy as np
import pandas as pd
# Prepare data - ALWAYS add constant for intercept
X = sm.add_constant(X_data)
# Fit OLS model
model = sm.OLS(y, X)
results = model.fit()
# View comprehensive results
print(results.summary())
# Key results
print(f"R-squared: {results.rsquared:.4f}")
print(f"Coefficients:\\n{results.params}")
print(f"P-values:\\n{results.pvalues}")
# Predictions with confidence intervals
predictions = results.get_prediction(X_new)
pred_summary = predictions.summary_frame()
print(pred_summary) # includes mean, CI, prediction intervals
# Diagnostics
from statsmodels.stats.diagnostic import het_breuschpagan
bp_test = het_breuschpagan(results.resid, X)
print(f"Breusch-Pagan p-value: {bp_test[1]:.4f}")
# Visualize residuals
import matplotlib.pyplot as plt
plt.scatter(results.fittedvalues, results.resid)
plt.axhline(y=0, color='r', linestyle='--')
plt.xlabel('Fitted values')
plt.ylabel('Residuals')
plt.show()
from statsmodels.discrete.discrete_model import Logit
# Add constant
X = sm.add_constant(X_data)
# Fit logit model
model = Logit(y_binary, X)
results = model.fit()
print(results.summary())
# Odds ratios
odds_ratios = np.exp(results.params)
print("Odds ratios:\\n", odds_ratios)
# Predicted probabilities
probs = results.predict(X)
# Binary predictions (0.5 threshold)
predictions = (probs > 0.5).astype(int)
# Model evaluation
from sklearn.metrics import classification_report, roc_auc_score
print(classification_report(y_binary, predictions))
print(f"AUC: {roc_auc_score(y_binary, probs):.4f}")
# Marginal effects
marginal = results.get_margeff()
print(marginal.summary())
from statsmodels.tsa.arima.model import ARIMA
from statsmodels.graphics.tsaplots import plot_acf, plot_pacf
# Check stationarity
from statsmodels.tsa.stattools import adfuller
adf_result = adfuller(y_series)
print(f"ADF p-value: {adf_result[1]:.4f}")
if adf_result[1] > 0.05:
# Series is non-stationary, difference it
y_diff = y_series.diff().dropna()
# Plot ACF/PACF to identify p, q
fig, (ax1, ax2) = plt.subplots(2, 1, figsize=(12, 8))
plot_acf(y_diff, lags=40, ax=ax1)
plot_pacf(y_diff, lags=40, ax=ax2)
plt.show()
# Fit ARIMA(p,d,q)
model = ARIMA(y_series, order=(1, 1, 1))
results = model.fit()
print(results.summary())
# Forecast
forecast = results.forecast(steps=10)
forecast_obj = results.get_forecast(steps=10)
forecast_df = forecast_obj.summary_frame()
print(forecast_df) # includes mean and confidence intervals
# Residual diagnostics
results.plot_diagnostics(figsize=(12, 8))
plt.show()
import statsmodels.api as sm
# Poisson regression for count data
X = sm.add_constant(X_data)
model = sm.GLM(y_counts, X, family=sm.families.Poisson())
results = model.fit()
print(results.summary())
# Rate ratios (for Poisson with log link)
rate_ratios = np.exp(results.params)
print("Rate ratios:\\n", rate_ratios)
# Check overdispersion
overdispersion = results.pearson_chi2 / results.df_resid
print(f"Overdispersion: {overdispersion:.2f}")
if overdispersion > 1.5:
# Use Negative Binomial instead
from statsmodels.discrete.count_model import NegativeBinomial
nb_model = NegativeBinomial(y_counts, X)
nb_results = nb_model.fit()
print(nb_results.summary())
Comprehensive suite of linear models for continuous outcomes with various error structures.
Available models:
Key features:
When to use: Continuous outcome variable, want inference on coefficients, need diagnostics
Reference: See references/linear_models.md for detailed guidance on model selection, diagnostics, and best practices.
Flexible framework extending linear models to non-normal distributions.
Distribution families:
Link functions:
Key features:
When to use: Non-normal outcomes, need flexible variance and link specifications
Reference: See references/glm.md for family selection, link functions, interpretation, and diagnostics.
Models for categorical and count outcomes.
Binary models:
Multinomial models:
Count models:
Key features:
When to use: Binary, categorical, or count outcomes
Reference: See references/discrete_choice.md for model selection, interpretation, and evaluation.
Comprehensive time series modeling and forecasting capabilities.
Univariate models:
Multivariate models:
Advanced models:
Key features:
When to use: Time-ordered data, forecasting, understanding temporal dynamics
Reference: See references/time_series.md for model selection, diagnostics, and forecasting methods.
Extensive testing and diagnostic capabilities for model validation.
Residual diagnostics:
Influence and outliers:
Hypothesis testing:
Multiple comparisons:
Effect sizes and power:
Robust inference:
When to use: Validating assumptions, detecting problems, ensuring robust inference
Reference: See references/stats_diagnostics.md for comprehensive testing and diagnostic procedures.
Statsmodels supports R-style formulas for intuitive model specification:
import statsmodels.formula.api as smf
# OLS with formula
results = smf.ols('y ~ x1 + x2 + x1:x2', data=df).fit()
# Categorical variables (automatic dummy coding)
results = smf.ols('y ~ x1 + C(category)', data=df).fit()
# Interactions
results = smf.ols('y ~ x1 * x2', data=df).fit() # x1 + x2 + x1:x2
# Polynomial terms
results = smf.ols('y ~ x + I(x**2)', data=df).fit()
# Logit
results = smf.logit('y ~ x1 + x2 + C(group)', data=df).fit()
# Poisson
results = smf.poisson('count ~ x1 + x2', data=df).fit()
# ARIMA (not available via formula, use regular API)
# Compare models using AIC/BIC
models = {
'Model 1': model1_results,
'Model 2': model2_results,
'Model 3': model3_results
}
comparison = pd.DataFrame({
'AIC': {name: res.aic for name, res in models.items()},
'BIC': {name: res.bic for name, res in models.items()},
'Log-Likelihood': {name: res.llf for name, res in models.items()}
})
print(comparison.sort_values('AIC'))
# Lower AIC/BIC indicates better model
# For nested models (one is subset of the other)
from scipy import stats
lr_stat = 2 * (full_model.llf - reduced_model.llf)
df = full_model.df_model - reduced_model.df_model
p_value = 1 - stats.chi2.cdf(lr_stat, df)
print(f"LR statistic: {lr_stat:.4f}")
print(f"p-value: {p_value:.4f}")
if p_value < 0.05:
print("Full model significantly better")
else:
print("Reduced model preferred (parsimony)")
from sklearn.model_selection import KFold
from sklearn.metrics import mean_squared_error
kf = KFold(n_splits=5, shuffle=True, random_state=42)
cv_scores = []
for train_idx, val_idx in kf.split(X):
X_train, X_val = X.iloc[train_idx], X.iloc[val_idx]
y_train, y_val = y.iloc[train_idx], y.iloc[val_idx]
# Fit model
model = sm.OLS(y_train, X_train).fit()
# Predict
y_pred = model.predict(X_val)
# Score
rmse = np.sqrt(mean_squared_error(y_val, y_pred))
cv_scores.append(rmse)
print(f"CV RMSE: {np.mean(cv_scores):.4f} ± {np.std(cv_scores):.4f}")
sm.add_constant() unless excluding intercept.summary() for detailed outputThis skill includes comprehensive reference files for detailed guidance:
Detailed coverage of linear regression models including:
Complete guide to generalized linear models:
Comprehensive guide to discrete outcome models:
In-depth time series analysis guidance:
Comprehensive statistical testing and diagnostics:
When to reference:
Search patterns:
# Find information about specific models
grep -r "Quantile Regression" references/
# Find diagnostic tests
grep -r "Breusch-Pagan" references/stats_diagnostics.md
# Find time series guidance
grep -r "SARIMAX" references/time_series.md
sm.add_constant() unless no intercept desiredFor detailed documentation and examples:
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