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zhangtaolab/PlantHelixSeek-lncRNA
PlantHelixSeek-lncRNA is a text classification model from zhangtaolab. Use it when you need a label for a piece of text. It is set up for transformers. The card lists the license as cc-by-nc-4.0.
Fine-tuned checkpoint of PlantHelixSeek (470M parameters) for binary classification of long non-coding RNAs.
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From the Hugging Face model README
Fine-tuned checkpoint of PlantHelixSeek (470M parameters) for binary classification of long non-coding RNAs.
The checkpoint uses the released train.csv, dev.csv and test.csv splits of plant-multi-species-lncRNAs (40,248 / 5,028 / 5,032 sequences). The source of the dataset is described on its dataset card.
| Setting | Value |
|---|---|
| Base model | PlantHelixSeek-470M |
| Epochs | 3 |
| Learning rate | 2e-5 |
| Per-device batch size | 1 |
| Gradient accumulation | 16 |
| Effective batch size | 16 |
| Warm-up ratio | 0.1 |
| Weight decay | 0.01 |
| Scheduler | linear |
| Optimizer | AdamW (fused) |
| Precision | bf16 |
| Gradient clipping | 1.0 |
| Seed | 42 |
| Hardware | one NVIDIA GPU |
| Training loss | 0.293 |
| Training time | 1.8 h |
Metrics on the held-out dev.csv split (the split used for checkpoint selection).
| Metric | Value |
|---|---|
| f1 | 0.904 |
| AUROC | 0.946 |
| AUPRC | 0.946 |
| mcc | 0.775 |
| accuracy | 0.890 |
from transformers import AutoModelForSequenceClassification, AutoTokenizer
model = AutoModelForSequenceClassification.from_pretrained(
"zhangtaolab/PlantHelixSeek-lncRNA", trust_remote_code=True
)
tokenizer = AutoTokenizer.from_pretrained(
"zhangtaolab/PlantHelixSeek-lncRNA", trust_remote_code=True
)
Always pass trust_remote_code=True; the HelixSeek architecture is registered through the Hugging Face auto_map mechanism.
Wu Y, He Y, Chen L, Liu Y, Wang T, Zhao H, Zhang Y, Zhang T. PlantHelixSeek learns transferable genome representations that capture conserved genome grammar for functional interpretation across plant species. Molecular Plant, 2026. Manuscript MOLECULAR-PLANT-D-26-00999 (DOI to be assigned).
Dataset source: Liu et al., Molecular Plant 2025; Mendoza-Revilla et al., Communications Biology 2024, doi:10.1038/s42003-024-06465-2.
CC-BY-NC 4.0 (research use; contact the authors for commercial licensing).