trialmatchai-gemma2-reranker-lora

TrialMatchAI · gemma-2-2b criterion reranker adapter (LoRA)

A LoRA adapter for the google/gemma-2-2b family, fine-tuned for the second-level criterion reranking stage of TrialMatchAI, an end-to-end system that matches patients to the clinical trials they are eligible for.

After first-level retrieval surfaces candidate trials, this adapter scores each (patient, trial criterion) pair so the most relevant trials are reranked to the top and shortlisted for the downstream eligibility-reasoning stage.

Usage

TrialMatchAI loads this adapter automatically. In config.json it sits on top of the instruct base:

"reranker_model_path": "google/gemma-2-2b-it",
"reranker_adapter_path": "majdabd33/trialmatchai-gemma2-reranker-lora"

It downloads on first use, so no separate model download step is needed. See the TrialMatchAI repository for the full pipeline and configuration.

Base model and license

This is an adapter of google/gemma-2-2b, governed by the Gemma license; accept it on the base model page before use. For research and informational use only. It is not medical advice, not a medical device, and must not replace review by qualified healthcare professionals.

Citation

Abdallah, M. et al. TrialMatchAI: an end-to-end AI-powered clinical trial recommendation system to streamline patient-to-trial matching. Nature Communications 17, 4472 (2026). https://doi.org/10.1038/s41467-026-70509-w