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esmc-300m-2024-12
daylight-00/esmc-300m-2024-12
esmc-300m-2024-12 is a machine learning model from daylight-00. Use it for the machine learning task on the model card, and read the license before you ship it in a product. The card lists the license as mit.
This is a copy of the ESMC 300M weights, kept so that PREpiBind has a pinned, always-available backbone. The weights are not ours. The upstream release is biohub/esmc-300m-2024-12; prefer it.
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Public
Updated Sep 10, 2026
Repo size
2.4 GB
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Repo makeup
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.pth1.3 GB · 100%
At a glance
- License
- mit
- Access
- Public
- Created
- Jun 3, 2025
- Updated
- Sep 10, 2026
- SHA
- b8bb1ad2
Model card
From the Hugging Face model README
ESMC 300M — a mirror, for PREpiBind
This is a copy of the ESMC 300M weights, kept so that
PREpiBind has a pinned, always-available backbone.
The weights are not ours. The upstream release is
biohub/esmc-300m-2024-12; prefer it.
| file | what it is |
|---|---|
esmc_300m_2024_12_v0_fp16.pth | the 308-tensor state_dict PREpiBind loads, float16 |
esmc_300m_2024_12_v0_bf16.pth | the same weights in bfloat16 |
emb_hla_esmc_small_0601_fp16.h5, emb_hla_esmc_small_light_0601_fp16.h5 | pre-computed HLA embeddings for the PREpiBind web server, not for the paper. The paper's stores are at daylight-00/prepibind-embeddings (research, full-length) and inside the GitHub repository (demo, 116 alleles). |
Licence
MIT. ESMC moved to Chan Zuckerberg Biohub and was relicensed: esm 3.4.0 ships a plain MIT
LICENSE.md ("Copyright 2026 Chan Zuckerberg Biohub, Inc."), and the upstream weights repo
EvolutionaryScale/esmc-300m-2024-12 now redirects to biohub/esmc-300m-2024-12, ungated, tagged
mit + other. This card previously said other / cambrian-open-license; that was correct when
it was written and is no longer. Checked 2026-09-10.
Citation
Cite ESMC as EvolutionaryScale / Chan Zuckerberg Biohub ask, and PREpiBind separately.
- License
- mit
- Created
- Jun 3, 2025
- Updated
- Sep 10, 2026